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This suggests that lipophagy may influence B-cell activity via ferroptosis, a hypothesis that requires further validation

"The big question for me is cancer

Although in cognitively healthy individuals differences in BBB uptake have been observed with APOE genotypes as early as in individuals in their 30s (Yassine et al., 2017) in mice older ages may be required for such disturbances to occur (Alata et al., 2015)