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Activation of oxidative stress response in cancer generates a druggable dependency on exogenous non-essential amino acids

Additionally, newly synthesized fisetin derivatives demonstrated stronger inhibition of NF-B, inflammasome, and ER stress pathways with reduced cytotoxicity [72]

Baserga R

Editor's note: This article has been edited to indicate that 23andMe is reducing the size of its therapeutics team, particularly its therapeutics discovery subgroup.