iih glp-1 Exenatide (a receptor agonist) rapidly lowered intracranial pressure in active IIH, with a sustained signal at 12 weeks and no meaningful weight change. The authors suggest an ICP-lowering Journal club: GLP-1 receptor agonists
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Journal club: GLP 1 receptor agonists in idiopathic intracranial hypertension Practical Neurology Impact of GLP 1 receptor agonists on idiopathic intracranial hypertension clinical and neurosurgical outcomes: a propensity matched multi institutional cohort study in: Journal of Neurosurgery Volume 143 Issue 4 (2025) Journals Treatment with GLP 1 receptor agonists is associated with significant weight loss and favorable headache outcomes in idiopathic intracranial hypertension The Journal of Headache and Pain Springer Nature Link glp 1 receptor agonists in idiopathic intracranial hypertension Proposed pathophysiological mechanisms underlying IIH and the target
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