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compounded tirzepatide A note on compounded meds: The FDA has issued cautions regarding compounded GLP-1 medications due to risks like contamination, incorrect concentrations, and temperature mishandling that can affect effectiveness

In 2012 the calculation of the response rates was adjusted to be slightly more conservative than previous years

As of early 2024, a federal panel has consolidated at least 55 lawsuits into a multidistrict litigation (MDL) in the Eastern District of Pennsylvania

The GLP-1RAs should not be restarted if pancreatitis is confirmed (Wharton et al., 2022), and none of the patients from the case series were rechallenged with GLP-1 RAs for safety reasons