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All of the above etiologies can lead to chronic oxidative stress (OS) state that causes melanocytes to be programmed for cellular senescence

Akkermansia Muciniphila and gut immune system: a good friendship that attenuates inflammatory bowel disease, obesity, and diabetes

[DOI] [PMC free article] [PubMed] [Google Scholar] Lachman HM, Papolos DF, Saito T, Yu YM, Szumlanski CL, Weinshilboum RM (1996) Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders