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To confirm the contribution of zonulin to early permeability changes in celiac disease, 20 patients on a gluten-free diet were randomized to a 3-day larazotide (12 mg once daily) or placebo treatment with a 2.5 g oral gluten challenge on the second day (96)

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While several compounds are promoted via social media claiming benefits of tissue repair, skin rejuvenation and anti-aging, we are particularly alarmed by the number of patients in our public multidisciplinary obesity clinic admitting to the use of unregulated products for weight loss, presumed to be pharmaceutical grade glucagon-like peptide-1 receptor agonists (GLP-1RA)