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In primary mouse adipocyte cultures, MR stimulation with aldosterone resulted in an increased pro-inflammatory and obesogenic adipokine profile including elevated leptin, IL-6, PAI-1, and chemerin (109)

In this mini-review, Emma Boretti, Jean-Michel Dogn and I critically examined the clinical, regulatory and mechanistic evidence surrounding a potential neoplasm signal observed during the development of fezolinetant, a first-in-class neurokinin 3 receptor antagonist approved for moderate-to-severe vasomotor symptoms associated with menopause

Patients experiencing fever with severe abdominal pain, jaundice, or signs of allergic reaction should seek urgent medical attention

Always store between 2-8C