TGF beta RII(Phospho Ser225) Polyclonal Antibody, 50ul Cell Dissociation Numerous alternatively spliced transcript variants

Numerous alternatively spliced transcript variants encoding different isoforms have been described

This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds

and polymorphisms that alter expression of this gene may play a role in carcinogenesis

This protein can form homodimers or can heterodimerize with another photoreceptor| retinal degeneration slow (RDS)

TGF beta RII(Phospho Ser225) Polyclonal Antibody, 50ul Cell Dissociation Numerous alternatively spliced transcript variantsThis gene encodes a member of the Ser Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF beta. This receptor ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have