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Phospho-BRCA1 (S1423) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Each of the three genes

SKU: 48955833403

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Phospho-BRCA1 (S1423) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Each of the three genesBRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein

The expression of TNFAIP2 was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein

CGGBP1 (CGG triplet repeat binding protein 1) influences expression of the FMR1 gene (MIM 309550)

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Phospho-BRCA1 (S1423) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Each of the three genesBRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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