NF-κB p105 (Cleaved-Thr434) Rabbit Polyclonal Antibody, 50ul Stepper Unlike the other two isoforms|

Unlike the other two isoforms| p46Shc is targeted to the mitochondrial matrix

and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription

2000 [PubMed 10673339])

and regulates the transcription of multiple genes including C-type natriuretic peptide

NF-κB p105 (Cleaved-Thr434) Rabbit Polyclonal Antibody, 50ul Stepper Unlike the other two isoforms|Glycine rich region (GRR) appears to be a critical element in the generation of p50. The C terminus of p105 might be involved in cytoplasmic retention inhibition of DNA binding and transcription activation. NF kappa B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation immunity differentiation cell growth tumorigenesis and apoptosis. NF kappa B is a homo or