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Nanog P8 Polyclonal Antibody, 100ul Cell Biology More variants exist| but their

SKU: 75217802004

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Nanog P8 Polyclonal Antibody, 100ul Cell Biology More variants exist| but theirThis locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a

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Description

More variants exist| but their full-length natures have yet to be determined

The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus

HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules

RNA-binding

Nanog P8 Polyclonal Antibody, 100ul Cell Biology More variants exist| but theirThis locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a

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