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At the same time, it has a similar function to GPX7, which can increase the PDI activity of ER redox protein 1 (ERO1), promote the oxidative folding of endoplasmic reticulum proteins, and reduce oxidative stress (Raykhel et al., 2007)

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The activity of blood SOD was increased significantly to reach normal or about normal values following the administration of H.pylori eradication therapy or nizatidine in combination with either vitamin E, thioctic acid or a combination of both agents.The normalization and /or significant elevation of blood SOD activity in H.pylori -infected duodenal ulcer patients may be attributed to the capacity of antioxidant vitamins to scavenge H.pylori -generated H 2 O2 and superoxide anion radicals thus saving SOD activity [75]

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