KALIG-1 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging Mammals possess four similar homeobox

Mammals possess four similar homeobox gene clusters| HOXA| HOXB| HOXC and HOXD| which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem

The protein encoded by this gene binds to the ETS2 promoter and is a strong repressor of ETS2 transcription

Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways

SLC52A2 has higher expression in brain tissue than small intestine

KALIG-1 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging Mammals possess four similar homeoboxMutations in KAL1 cause the X linked Kallmann syndrome. Anosmin 1 is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N glycosylated and may have anti protease activity.