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Smad1/5/9 Polyclonal Antibody, 20ul[BT-AP14289] Polyclonal Antibody Preparation The protein is primarily expressed

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Smad1/5/9 Polyclonal Antibody, 20ul[BT-AP14289] Polyclonal Antibody Preparation The protein is primarily expressedThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell

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Description

The protein is primarily expressed in placental and endometrial tissue| however

the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat

The AP-3 complex plays a role in protein trafficking to lysosomes and specialized organelles

Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches

Smad1/5/9 Polyclonal Antibody, 20ul[BT-AP14289] Polyclonal Antibody Preparation The protein is primarily expressedThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell

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