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Similarly, many Gram-positive bacteria chromosomally encode efflux pumps that expel certain antibiotics, such as fluoroquinolones and macrolides

Wainwright MS, Kohli R, Whitington PF, Chace DH

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In summary, as conserved cysteine residues are potential candidates for the redox control of proteins due to their ability to undergo reversible oxidation-reduction reactions, participate in enzyme catalysis, maintain structural integrity, and sense the cellular redox environment, Cys190 conservation across different species underscores its essential role in GSAAT enzyme catalysis or its regulatory function ( Supplementary Figure 1 )