EDEM3 Polyclonal Antibody, 50ul Proteases The encoded protein is activated

The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation

Mutations in CYP1B1 have been associated with primary congenital glaucoma

Catalytic activity:Cleavage of Arg-|-Ala bond in complement component C4 to form C4a and C4b| and Lys(or Arg)-|-Lys bond in complement component C2 to form C2a and C2b: the 'classical' pathway C3 convertase

thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site

EDEM3 Polyclonal Antibody, 50ul Proteases The encoded protein is activatedQuality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006