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ABT-492 Catalog No.:M7915-10 5R)-3-hydroxy-3-methyl-8-azabicyclo[3

SKU: 16820036799

4.4
USD90.00 USD125.00

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ABT-492 Catalog No.:M7915-10 5R)-3-hydroxy-3-methyl-8-azabicyclo[3ABT 492 is a non zwitterionic fluoroquinolone antibiotic under development for for the treatment of respiratory and skin infections. Delafloxacin demonstrates excellent antibacterial potency and exhibits a low probability for the selection of resistant mutants in MRSA. Although mutants can be selected at low frequencies in vitro from quinolone resistant isolates, delafloxacin MICs and MPCs remain low and a fitness cost can be observed. Consequently

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Description

5R)-3-hydroxy-3-methyl-8-azabicyclo[3

Inhibits GTP binding to CB1-overexpressing cell membranes in vitro (EC50 = 18

PF-04457845 is completely selective for FAAH

Epub 2019 Mar 31

ABT-492 Catalog No.:M7915-10 5R)-3-hydroxy-3-methyl-8-azabicyclo[3ABT 492 is a non zwitterionic fluoroquinolone antibiotic under development for for the treatment of respiratory and skin infections. Delafloxacin demonstrates excellent antibacterial potency and exhibits a low probability for the selection of resistant mutants in MRSA. Although mutants can be selected at low frequencies in vitro from quinolone resistant isolates, delafloxacin MICs and MPCs remain low and a fitness cost can be observed. Consequently

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