PP4R1 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging An allelic polymorphism in FCGR2C

An allelic polymorphism in FCGR2C results in both coding and non-coding variants

Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration

Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1

May also be involved in the regulation of gene expression

PP4R1 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging An allelic polymorphism in FCGR2CThis gene encodes one of several alternate regulatory subunits of serine threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.