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Hypoxia induces proliferation via NOX4-Mediated oxidative stress and TGF-beta3 signaling in uterine leiomyoma cells

Frazier, Ph.D., and Rabindra Tirouvanziam, Ph.D

Looking ahead, improving tissue- or cell-specific vector targeting, building high-throughput screening platforms for FAD-sensitive variants, and using patient-derived iPSC neurons for personalized preclinical testing will be pivotal in transitioning from experimental use to clinical implementation of integrated nutrient plus gene-editing therapies