Gemcitabine - CAS# 95058-81-4 Catalog No.:M10648-2 Molecular Weight: 425
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Gemcitabine - CAS# 95058-81-4 Catalog No.:M10648-2 Molecular Weight: 425Gemcitabine is an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Product information CAS
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