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In rare situations, B12 shots itching rash anaphylaxis, a life threatening condition that can cause a fast heartbeat and difficulty breathing Other side effects that can occur include: shortness of breath, fast weight gain, and swelling congestive heart failure, the inability of the heart to adequately pump blood pulmonary edema, the buildup of fluid in the lungs peripheral vascular thrombosis, the obstruction of a vein with a blood clot hypokalemia, low potassium levels that can cause irregular heartbeats and muscle weakness fever tingling, numbness, and joint pain swollen tongue polycythemia, an increase in the red blood cell mass Additionally, B12 B12 shots are not necessary for weight loss

Most common route Oral capsule, 50 to 150 mg per day, taken in the morning

Cyanocobalamin is substantially less expensive to manufacture and is the form most commonly used in fortified foods and many supplements

If B12 levels were low to begin with, longer-term benefits like red blood cell production or nervous system support may take several weeks