ADC Toxin Monomethyl auristatin F (MMAF) - CAS# 745017-94-1 Catalog No.:T60002-10S Formula: C18H17ClN2O3S

Formula: C18H17ClN2O3S

is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM

activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay

2 mg solid each for the following compounds:

ADC Toxin Monomethyl auristatin F (MMAF) - CAS# 745017-94-1 Catalog No.:T60002-10S Formula: C18H17ClN2O3SMMAF (Monomethylauristatin F) , CAS No. 745017 94 1, is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN CD19A. Product information CAS Number: 745017 94 1 Molecular Weight: 731. 96 Formula: C39H65N5O8 Chemical Name: (S) 2 ((2R,3R) 3 ((S) 1 ((3R,4S,5S) 4 ((S) N,3 dimethyl 2 ((S) 3