Miltefosine - CAS# 58066-85-6 Catalog No.:M11118-10 Chaudhuri D

Chaudhuri D

>5000 mg/kg bwt by the dermal route

Vinflunine inhibits tubulin assembly without any stablization of assembled microtubules at concentrations comparable to those of other vinca alkaloids such as vincristine

128(48):15529-36

Miltefosine - CAS# 58066-85-6 Catalog No.:M11118-10 Chaudhuri DMiltefosine is an orally and topically active alkyl phosphocholine compound with potential antineoplastic activity. Miltefosine targets cellular membranes, modulating cell membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti apoptotic mitogen activated protein kinase (MAPK) pathway and modulates