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LX-1031 - CAS# 945976-76-1 Catalog No.:M10754-2 Molecular Weight: 194

LX-1031 - CAS# 945976-76-1 Catalog No.:M10754-2 Molecular Weight: 194

Name: LX-1031 - CAS# 945976-76-1 Catalog No.:M10754-2 Molecular Weight: 194
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SKU: 63606405032
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LX-1031 - CAS# 945976-76-1 Catalog No.:M10754-2 Molecular Weight: 194LX 1031 is a THP inhibitor (a tryptophan 5 hydroxylase inhibitor) that reduces 5 HT levels for the potential treatment of irritable bowel syndrome. LX 1031 has potential for illnesses characterized by excess 5 HT, such as diarrhea predominant irritable bowel syndrome (IBS D) and carcinoid diarrhea. In vitro, inhibition of TPH1 occurred in 10( 8) 10( 7) mol L( 1) range. In vivo in rodents, LX 1031 has no effect on brain 5 HT while dose dependently

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Description

Molecular Weight: 194

InChi: InChI=1S/C24H18N4O/c1-27-17-9-4-2-7-14(17)20-21-16(13-26-24(21)29)19-15-8-3-5-10-18(15)28(12-6-11-25)23(19)22(20)27/h2-5

PubMed PMID: 26185454

InChiKey: NQHWMFGCRBTMOO-DWCMLEBJSA-N

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